ÐÏࡱá>þÿ 8:þÿÿÿ7ÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿì¥ÁW ð¿bjbjfýfý 4(—“i—“i ÿÿÿÿÿÿ·..ÁÁÁÁÁÿÿÿÿÕÕÕ8 ,9ÕW&MMMMM���ÖØØØØØØ$}¶3"êüÁ�����üÁÁMM4ÃÃÃ�ÁMÁMÖÃ�ÖÃâîMÿÿÿÿ€l¤åZÚÿÿÿÿ�@ºÂ'0WÂ,#ݲ#î#ÁîÔ��Ã�����üü�4���W����ÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ#���������.Y ‡: Format for IPBS Qualifying Examination (Grant Writing Exercise) Page size: 8 ½ x 11 inches Font: Arial 11 or 12 point, black (smaller font sizes are allowed in figures and legends as long as they are legible) Margins: at least 0.5 inch top, bottom, left, right Header: Student’s name, “IPBS Qualifying Examination”, Month, Year Footer: page number (number consecutively starting with 1 on the first page) Language: English (avoid jargon) Page limits (double spaced): Specific Aims 2 pages Research Strategy 18 pages Literature Cited no page limit General format: The Specific Aims Page should include an introduction explaining the context of the proposed research and the broad, long-term objectives, making reference to the health relatedness of the research. Provide a strong rationale supporting your hypothesis. This rationale will explain the logic behind your reasons for proposing your specific hypothesis. Next, state the goal(s) of the specific research proposed, e.g., to test a stated hypothesis, create a novel design, solve a specific problem, challenge an existing paradigm or clinical practice, address a critical barrier to progress in the field, or develop new technology. The “Specific Aims” should then be enumerated with an indication of the strategies proposed for achieving the goals(s), including a brief description of the types of methods that will be employed. The Research Strategy should include background information leading to the proposed research, the significance of the research, and the research approach (design and methods) for achieving the Specific Aims. The information may be organized into the following sections: A “Background & Significance” section should be a brief sketch of the background leading to the present application. Critically evaluate existing knowledge and specifically identify the gaps that the project is intended to fill. State concisely the importance and health relevance of the research described in this application by relating the specific aims to broad, long-term objectives and to the mission of the NIH. An “Innovation” paragraph should be included at the end of this section to describe what new critical information will be obtained from your studies. “Preliminary Studies” – For this exercise, a description of preliminary studies is not required, but it may be beneficial to include pertinent data from the literature (with appropriate citations) to support the hypotheses under investigation and/or the feasibility of the approach. “Research Design and Methods” – This section is a description of the research design conceptual or clinical framework, procedures, and analyses to be used to accomplish the specific aims of the project. Include how the data will be collected, analyzed, and interpreted. Provide a specific rationale for each set of experiments and include expected/alternative outcomes of the proposed studies. Describe any new methodology and its advantage over existing methodologies. Describe any novel concepts, approaches, tools, or technologies for the proposed studies. Discuss the potential difficulties and limitations of the proposed procedures and alternative approaches to achieve the aims. As part of this section, provide a tentative sequence or timetable for the project. Point out any procedures, situations, or materials that may be hazardous to personnel and the precautions to be exercised. The Literature Cited section should provide complete references. For journal articles include all authors, title, journal name, page numbers, and year of publication. A consistent format should be used throughout the document. The proposed research may involve the use of vertebrate animals or human subjects. Although not required for this exercise, be aware that an actual research proposal involving animals or human subjects would require additional detailed sections describing the specifics of their intended use, justification for their inclusion, as well as approval by the respective compliance committees of the university (IACUC and IRB, respectively).     -./?@A\]ÓÔ " ' 6 = L š › ¼ ½ È Ø Ú Û ê ë ì ñ ò ó      $ % / 2 3 4 D E ñææñØËËËËËËËÁËÁËËËËË˷˪ˠ·Ë·ËË– · ËŒ– ––ËËËh>Uh'^:OJQJ^Jh>UOJQJ^Jh'^:OJQJ^Jh¸1éOJQJ^JhîRhîROJQJ^JhîROJQJ^Jh¯6þOJQJ^Jh>Uh>UOJQJ^Jh'^:hø#-5�OJQJ^Jh%!y5�OJQJ^Jh'^:h>U5�OJQJ^J-@A\]ÓÔ L š › ¼ ½ Û ó  3 4 D E € � ��÷õíííííííííííáíííííÕÕÕÕ $„Ð^„Ða$gdžmí $„Ð`„Ða$gdîR$a$gdžmí$a$gd'^:E I V X [ k w z ¯ Î Ï Ð  A ¦ ­ ² / º » ½ Õ Ú  ôâоô²¦²—²—ˆ¦|p|aTTaˆ²H²hûeœ@ˆOJQJ^JhOU•hOU•OJQJ^JhOU•hOU•@ˆOJQJ^Jhz'ë@ˆOJQJ^Jh/`@ˆOJQJ^JhOU•h'^:@ˆOJQJ^Jh'^:h'^:@ˆOJQJ^Jhg@ˆOJQJ^Jh'^:@ˆOJQJ^J"hè1h>U5�>*@ˆOJQJ^J"hè1hè15�>*@ˆOJQJ^J"h>Uh>U5�>*@ˆOJQJ^Jh>U@ˆOJQJ^J 0 > C ~  € � … – /QŽ��/235ÉÊËÌ+ôèØèɺ®Ÿ�Ÿ�ŸŸ�®ttjj`jSIttth%!yOJQJ^Jh2eh2eOJQJ^JhÇ}OJQJ^Jh2eOJQJ^Jha:ŽhOU•OJQJ^Jha:Ž@ˆOJQJ^J"h>Uh>U5�>*@ˆOJQJ^Jh>Uh>U@ˆOJQJ^Jh>U@ˆOJQJ^Jh'^:h>U@ˆOJQJ^Jh'^:h'^:@ˆOJQJ^JhÙA«h'^:>*@ˆOJQJ^Jh'^:@ˆOJQJ^JhOU•@ˆOJQJ^J�ËÌèéfgJK    óóóóóççßßÚØÚØÚØÚØØßgdR¸$a$gdžmí $„Ð^„Ða$gdžmí $„ ^„ a$gdžmí+2 ÅÉÊçèéêÊõ÷/0q0efgk{¦IJKxóäÕÉÕä¼¼ó¼ó¼¼ó­¡­¼¼ä••ƒ•wj]ShžmíOJQJ^Jh>Uh>UOJQJ^Jh>Uh'^:OJQJ^JhOU•@ˆOJQJ^J"hOU•h'^:5�>*@ˆOJQJ^Jh'^:@ˆOJQJ^Jh%!y@ˆOJQJ^Jha:Žha:Ž@ˆOJQJ^Jha:ŽhOU•OJQJ^JhÌ Æ@ˆOJQJ^Jha:ŽhÌ Æ@ˆOJQJ^Jha:ŽhOU•@ˆOJQJ^Jha:Žha:ŽOJQJ^Jxœ�ž§ÅÇÕ#.07JK\àþÿ     óéóéÛóéóéóóéóÑóéó¼¸¸¼¸¸¼¸¸¸Äh¶wFjh¶wFUhžmíh>UOJQJ^Jh^lIOJQJ^Jhžmíhžmí>*OJQJ^JhžmíOJQJ^JhžmíhžmíOJQJ^J 21�h:p¶wF°Ð/ °à=!° "° #� $� %°°Ð°Ð �Ðx2ÆÖæö&6FVfv†–ÆÖæö2(Øè&6FVfv†–ÆÖæö&6FVfv†–ÆÖæö&6FVfv†–ÆÖæö&6FVfv†–ÆÖæö&6FVfv†–ÆÖæö&6FVfv†–8XøV~� °ÀЀàð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@àð 0@66666_HmH nH sH tH @`ñÿ@ NormalCJ_HaJmH sH tH DA òÿ¡D Default Paragraph FontRióÿ³R  Table Normalö4Ö l4Öaö (k ôÿÁ(No List bþ/ñÿòb îRDefault 7$8$H$-B*CJOJQJ^J_HaJmH phsH tH H™H g Balloon TextCJOJQJ^JaJNþ/òÿN gBalloon Text CharCJOJQJ^JaJPK!éÞ¿ÿ[Content_Types].xml¬‘ËNÃ0E÷Hüƒå-Jœ²@%é‚ÇŽÇ¢|ÀÈ™$ÉØ²§Uû÷LÒTB¨ l,Ù3÷ž;ãr½µÃ˜œ§J¯òB+$ëG]¥ß7OÙ­V‰� (¼ÑBOÀ)êMØB¥Tª.$@Ó0H!Aµûý>í’ £U†ëcå-†—©’z¡ËD[«&Ž„ÁöŽË!‡r“‰àX=Ä}zü´Cž©0` Þ¨‡%ó.¬ß]€µ‘Ssd-¹-ó7’ ôŽ+fO›–Z•Õ¥r¡ß˜šÅµVõ¡Ï ÛÅ“æ\l�ååjiµ2ÂZ ü§Gwm¥¼èâ-ý‹3œËµj£²äè7 \ÿÒ ¾´Uk5—¼åøåüF©Ò¨-:xÊñÕüRkc¥Òrð3šÏ¢«+««Õº€ô9ÛöÂkÕji¥9‚OP Eté-ú˜j|Àûƒ#‡p;E=ƉÜåœ5¸ðZá¡ÞË2sg�FþÍÅÀÆ=8ñí½ ©ãåÖ ÃK}*7câÐ<`�*ˆHJT ïñcB<§{J©c×]Ú\ò¾ žÒ Ôk’=t¢i"´MôËÐGýíØf÷IÐàÌwê&9q‘øló�ïæ˜ñ> $>•H˜mðP±�d{(º6®%z:"Œ­‘Ò'³/ð¼–Óf7¯ÛwÙ0q‘BÑcŸÎàÜF6ùñf IæÃ¶iÛØÏå1†(\ùà»Ü}Bô5úÒ¹î~B‰ãÁcÌr6¥I€è;áñå}Â�ømYˆ/ÕlˆÄI±‚z££1ˆœÐÞ!„Á)ô îaÐà™có é1f•mâ ¬àÆª¾N‰Ä^I77³yr‡J'dÛ$âsøì§ÏÒÄ<Í{èuÛæ­C�£‡Â>ëÛÀ=Š= Æ‹×(ûuXÁ=WëA NÓ×Ò¯Cáøï2Ï>—G�K<—(C®,ƒ‰Ý–ù m:Àœ &ÓìøÒ-Š8èâjÄ^¹¾ûÐN܀ݑÓô$4½ úï:ì/Îxå Á›évüŠ�TuÅ>²µ°÷*Ùžênæá¦{šM.³úôã´Ç¾±š0±á³ÕÁµ´¥³ÜÛÑÜv4áÿ¾£™÷<ßö1óº�Û>&Äþâ¶��Vn¦�™´.ØÕèñB>æ1CŸdî̧Ok«!#;ÒŒ}$¾Íô¶pQË™y')f€YŒ?u™Ã \$ÀÈ‚«/¨ŠÛ1d8*‡ZI$Gª#d\âÈÈ,{uk<$»¼—�:Íl©”WV j²^ZÆ¡S¾Žc*•£«+£EÍÏÌS‘¯a™1똀–½ k3—Ä¢‡ÄÊxñzjv3,j«ZýØU3¦@j…Wðu;À—ôz¸¼¤ áŒ\v±5ïi?å®{×8ó&==ϘNàX1? å O×4×¹ÇÓ§ËCížvH§äaå’0–1 žŒñ%x�zõ24®êëÚÄ¥=m ³Æ÷„ÆÊê‡X\××(7�Xjg –§õ°º¸Œ!Ó…¬öqdŒ?“ cGê7.`~wé*‘?ð×É,™�ª 2Î n’Nîž„*"F“z¨�_¸�¥&‡nå &„�–\ ÓÊÇF�î:™ôû¤«l·[+ÚÒù%fø 0(ÿÿÿÿ E  +x �ð@ð @ñÿÿÿ€€€÷ð’ ðð0ð( ð ððB ðS ð¿Ëÿ ?ððHðð0ð( ð ð$ / ¶Àæî-2Ðà3333-/A\›»ÚÚEEWXwzÂÂÃà ­ÕÚQ�2Ê/ 0 -/ÉÊ/ 0 ÿE[CšÀj¼ÿÿÿÿÿÿÿÿÿh„ „˜þÆ ^„ `„˜þOJQJo(‡hˆH§ð�h„p„˜þÆp^„p`„˜þOJQJ^Jo(‡hˆHo�h„@ „˜þÆ@ ^„@ `„˜þOJQJo(‡hˆH§ð�h„„˜þÆ^„`„˜þOJQJo(‡hˆH·ð�h„à„˜þÆà^„à`„˜þOJQJ^Jo(‡hˆHo�h„°„˜þư^„°`„˜þOJQJo(‡hˆH§ð�h„€„˜þÆ€^„€`„˜þOJQJo(‡hˆH·ð�h„P„˜þÆP^„P`„˜þOJQJ^Jo(‡hˆHo�h„ „˜þÆ ^„ `„˜þOJQJo(‡hˆH§ðE[Cÿÿÿÿÿÿÿÿ         /å.g>U3 È8ôa2eîR³e…4#ø#-è1'^:d[D¶wF^lI08R/`‘lVNx%!yÇ}ZiŠË|‹a:ŽOU•öf–}:˜¤>™ûeœÙA«R¸V¼_2ÁÌ ÆŠ~ÆÓOÊÛwΟyÖ ä¯kä kæ¸1éz'ëÆPìžmí¯6þš:ÿÿ@€/ / / / @ÿÿUnknownÿÿÿÿÿÿÿÿÿÿÿÿ G�ÿ.à[xÀ ÿTimes New Roman5�€Symbol3.� ÿ.à[xÀ ÿArial9.� ÿ.ääÀ ÿSegoe UIC.�‡ ŸAptos Display3.�‡ ŸAptos;�€Wingdings?=� ÿ.àCxÀ ÿCourier NewA�ÿàÿ$BŸCambria Math"1€ðÐhj*DG¶;Âgc� c� Áð  ´´��20øø 3ƒqðüý@P ðÿ?äÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ>U2!xx ó¬qH Üÿÿ?Format for IPBS Qualifying Examination (Grant-writing Exercise)Kenneth L. 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ByronNormalDenning, Mitchell4Microsoft Office Word@¤“Ö@¬…OI�Ñ@d[ÆZÚc� þÿ ÕÍÕœ.“—+,ù®0, hp€ˆ�˜  ¨°¸ À äLUHSø @Format for IPBS Qualifying Examination (Grant-writing Exercise) Title þÿÿÿ !"#$%&þÿÿÿ()*+,-.þÿÿÿ0123456þÿÿÿýÿÿÿ9þÿÿÿþÿÿÿþÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿRoot Entryÿÿÿÿÿÿÿÿ ÀFÔåZÚ;€1Tableÿÿÿÿÿÿÿÿ-#WordDocumentÿÿÿÿÿÿÿÿ4(SummaryInformation(ÿÿÿÿ'DocumentSummaryInformation8ÿÿÿÿÿÿÿÿÿÿÿÿ/CompObjÿÿÿÿÿÿÿÿÿÿÿÿrÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿþÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿþÿ ÿÿÿÿ ÀF Microsoft Word 97-2003 Document MSWordDocWord.Document.8ô9²q